CellNetOptimizer (CNO) is a MATLAB toolbox for creating logic-based models of signal transduction networks, and training them agains high-throughput biochemical data. CNO can be used independently, or together with DataRail a complementary MATLAB toolbox for managing, transforming and visualizing data.
CNO is free to download and use under the Creative Commons Attribution-No Derivative Works 3.0 United States License.
Please use the following citation to refer to CNO:
J. Saez-Rodriguez*, L. G. Alexopoulos*, J. Epperlein, R. Samaga, D. A. Lauffenburger, S. Klamt and P. K. Sorger. Discrete logic modeling as a means to link protein signaling networks with functional analysis of mammalian signal transduction, Molecular Systems Biology, 5:331, 2009. [* these authors contributed equally to this work]