Karen Sachs

RESEARCH AND PROFESSIONAL EXPERIENCE

Professional Experience:

1993-1997 Technion. B.S., Biology, Summa cum laude Research: Yeast genetics. Advisor: Dr. Yona Kassir

1997-1999 Mandatory military/civil service (Israeli army)

2004-2005 Internship, Aventis Pharmaceuticals. Research: Computational analysis of drug mechanism of action. Supervisor: Dr. Joachim Theilhaber

1999-present Ph.D. student, Division of Biological Engineering, Massachusetts Institute of Technology Research: Computational modeling of signal transduction pathways. Advisor: Dr. Douglas A. Lauffenburger

Honors and Fellowships:
Merck/MIT Bioinformatics Fellowship 2000-2002

Invited Speaker:

06/2004 Aventis Pharmaceuticals, Cambridge, MA
07/2004 Aventis Pharmaceuticals, Vitry, France
01/2005 Computational and Systems Biology Initiative Symposium, Cambridge, MA
04/2005 Millennium Pharmaceuticals, Cambridge, MA
06/2005 Molecular Sciences Institute Alpha Symposium, Berkeley, CA
06/2005 Vertex Pharmaceuticals, Cambridge, MA
08/2005 Pfizer Pharmaceuticals, Cambridge, MA
09/2005 Merrimack Pharmaceuticals Inc, Cambridge, MA
11/2005 Departmental Seminar, UCSF Department of Biochemistry and Biophysics, San Francisco, CA (scheduled)

Peer-reviewed publications:

1. Sachs K, Perez O, Pe'er D, Lauffenburger DA, Nolan GP. Causal protein-signaling networks derived from multiparameter single-cell data. Science. 2005 Apr 22;308(5721):523-9.

Invited (Non-peer-reviewed) Publications:

1. K. Sachs, D. Gifford, T. Jaakkola, P. Sorger and D.A. Lauffenburger. “Bayesian Network Approach to Cell Signaling Pathway Modeling.” Science STKE, Sep. 3, 2002, 148, pe38.

2. K. Sachs. “Bayesian Networks- A Quick Intro” Biomedical Computation Review, Summer, 2005, p31.