Jason Locasale

Education

PhD Candidate, Biological Engineering MIT

M.S. Chemistry, UC Berkeley, 2005

B.A. Chemistry, Physics Rutgers University, 2003

CDP research

Understanding design principles of biological networks and cell signaling processes pertinent to disease progression: emphases on models for T cell activation and the role of accessory proteins in MAPK signaling.

Selected Publications

Locasale JW. Shaw AS. Chakraborty AK. “Scaffold proteins confer diverse regulatory properties to protein kinase cascades” Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13307-12.

Locasale, JW. “Computational investigations into the origins of biochemical memory in T-cell activation” PLoS ONE 2007 Jul 18;2(7):e627

Cemerski S. Das J. Locasale J. Arnold P. Giurisato E. Markiewicz MA. Fremont D. Allen PM. Chakraborty AK. Shaw AS. “The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse” Immunity. Mar;26(3):345- 55. 2007