Doug Lauffenburger

Douglas A. Lauffenburger is Uncas & Helen Whitaker Professor of Bioengineering and Director of the Biological Engineering Division at MIT, and also holds appointments in the Department of Biology and the Department of Chemical Engineering. He is a member of the Biotechnology Process Engineering Center, Center for Biomedical Engineering, Center for Cancer Research, and Center for Environmental Health Sciences, and serves on the Steering Committee of the Computational & Systems Biology Initiative.

Dr. Lauffenburger’s BS and PhD degrees are in chemical engineering from the University of Illinois and the University of Minnesota, in 1975 and 1979 respectively. His major research interests are in cell engineering: the fusion of engineering with molecular cell biology. A central focus of his research program is in receptor-mediated cell communication and intracellular signal transduction, with emphasis on development of predictive computational models derived from quantitative experimental studies, for cell cue/signal/response relationships important in pathophysiology with application to drug discovery and development. Lauffenburger has coauthored a monograph entitled Receptors: Models for Binding, Trafficking & Signaling, published by Oxford University Press in 1993 and reprinted in 1996. More than 70 doctoral students and postdoctoral associates have completed their training under his supervision or co-supervision.

Prof. Lauffenburger has served as a consultant or scientific advisory board member for Astra-Zeneca, Beyond Genomics, CellPro, Eli Lilly, Entelos, Genstruct, Insert Therapeutics, Johnson & Johnson, Merrimack Pharmaceuticals, Pfizer, Precision Therapeutics, SyStemix, the Burroughs-Wellcome Fund, and the Whitaker Foundation. His awards include the A.P. Colburn Award, Bioengineering Division Award, and W.H. Walker Award from AIChE, the Distinguished Lecture Award from BMES, the C.W. McGraw Award from ASEE, the Amgen Award in Biochemical Engineering from the Engineering Foundation, and a J.S. Guggenheim Fellowship, along with a number of named lectures at academic institutions. He is a member of the National Academy of Engineering and of the American Academy of Arts & Sciences, and has served as President of the Biomedical Engineering Society, Chair of the College of Fellows of AIMBE, and on the Advisory Council for the National Institute for General Medical Sciences at NIH.