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"The focus on individual genes and proteins, which has proven so powerful for the molecular genetics of the past century, is in and of itself inadequite to the task of describing dynamic processes involving interactions among tens, hundreds and even thousands of components."
Dr. Peter Sorger, CDP Director |
Research & ScientistsBy systems biology we in the CDP Center mean the study of complex biological phenomena using a combination of experimental data, mathematical analysis and physiological insight.
The aim is to build formal numerical representations – models – of biological processes and to test the models experimentally. The numerical emphasis is important because only mathematical models have the power to capture the dynamic behavior of networks of interacting components. It is a truism that detailed knowledge of the parts comprising a system provides only limited insight into the dynamics of the system as a whole. |
  Cell death modeling.Genetics, cell biology, and biochemistry have been instrumental in identifying and organizing signaling proteins...
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